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CMPK2 and BCL-G are associated with type 1 interferon–induced HIV restriction in humans
Type 1 interferons (IFN) are critical for host control of HIV and simian immunodeficiency virus. However, it is unknown which of the hundreds of interferon-stimulated genes (ISGs) restrict HIV in vivo. We sequenced RNA from cells that support HIV replication (activated CD4(+) T cells) in 19 HIV-infe...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070316/ https://www.ncbi.nlm.nih.gov/pubmed/30083606 http://dx.doi.org/10.1126/sciadv.aat0843 |