Cargando…

CMPK2 and BCL-G are associated with type 1 interferon–induced HIV restriction in humans

Type 1 interferons (IFN) are critical for host control of HIV and simian immunodeficiency virus. However, it is unknown which of the hundreds of interferon-stimulated genes (ISGs) restrict HIV in vivo. We sequenced RNA from cells that support HIV replication (activated CD4(+) T cells) in 19 HIV-infe...

Descripción completa

Detalles Bibliográficos
Autores principales:	El-Diwany, Ramy, Soliman, Mary, Sugawara, Sho, Breitwieser, Florian, Skaist, Alyza, Coggiano, Candelaria, Sangal, Neel, Chattergoon, Michael, Bailey, Justin R., Siliciano, Robert F., Blankson, Joel N., Ray, Stuart C., Wheelan, Sarah J., Thomas, David L., Balagopal, Ashwin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070316/ https://www.ncbi.nlm.nih.gov/pubmed/30083606 http://dx.doi.org/10.1126/sciadv.aat0843

Ejemplares similares

Mitochondrial genome diversity and evolution in Branchiopoda (Crustacea)
por: Luchetti, Andrea, et al.
Publicado: (2019)

A Role for the Chicken Interferon-Stimulated Gene CMPK2 in the Host Response Against Virus Infection
por: Li, Xin, et al.
Publicado: (2022)

Erratum to: Are T cells the only HIV-1 reservoir?
por: Kandathil, Abraham Joseph, et al.
Publicado: (2017)

Are T cells the only HIV-1 reservoir?
por: Kandathil, Abraham Joseph, et al.
Publicado: (2016)

The mitochondrial gene-CMPK2 functions as a rheostat for macrophage homeostasis
por: Arumugam, Prabhakar, et al.
Publicado: (2022)

Loss of function of CMPK2 causes mitochondria deficiency and brain calcification
por: Zhao, Miao, et al.
Publicado: (2022)

CMPK2 restricts Zika virus replication by inhibiting viral translation
por: Pawlak, Joanna B., et al.
Publicado: (2023)

HIV and HCV Activate the Inflammasome in Monocytes and Macrophages via Endosomal Toll-Like Receptors without Induction of Type 1 Interferon
por: Chattergoon, Michael A., et al.
Publicado: (2014)

Functional Variants Associated With CMPK2 and in ASB16 Influence Bovine Digital Dermatitis
por: Oelschlaegel, Diana, et al.
Publicado: (2022)

Dracorhodin targeting CMPK2 attenuates inflammation: A novel approach to sepsis therapy
por: Zhang, Wendan, et al.
Publicado: (2023)

Data on the association of CMPK1 with clinicopathological features and biological effect in human epithelial ovarian cancer
por: Zhou, Daibing, et al.
Publicado: (2017)

CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway
por: Luo, Yunhai, et al.
Publicado: (2021)

Electroacupuncture Inhibits NLRP3 Activation by Regulating CMPK2 After Spinal Cord Injury
por: Chen, Yi, et al.
Publicado: (2022)

UMP/CMPK Is Not the Critical Enzyme in the Metabolism of Pyrimidine Ribonucleotide and Activation of Deoxycytidine Analogs in Human RKO Cells
por: Hu, Rong, et al.
Publicado: (2011)

Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways
por: Lai, Jenn-Haung, et al.
Publicado: (2021)

Maintenance of viral suppression in HIV-1–infected HLA-B*57(+) elite suppressors despite CTL escape mutations
por: Bailey, Justin R., et al.
Publicado: (2006)

CMPK1 Regulated by miR-130b Attenuates Response to 5-FU Treatment in Gastric Cancer
por: Chu, Huaizhu, et al.
Publicado: (2021)

CMPK2 is a host restriction factor that inhibits infection of multiple coronaviruses in a cell-intrinsic manner
por: Zhu, Mingjun, et al.
Publicado: (2023)

Physical and mental health disability associated with long-COVID: Baseline results from a US nationwide cohort
por: Lau, Bryan, et al.
Publicado: (2022)

Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing
por: Pham, Minh-Tam, et al.
Publicado: (2022)

CRISPR-Cas9 for selective targeting of somatic mutations in pancreatic cancers
por: Teh, Selina Shiqing K., et al.
Publicado: (2023)

Mitochondrial protein CMPK2 regulates IFN alpha-enhanced foam cell formation, potentially contributing to premature atherosclerosis in SLE
por: Lai, Jenn-Haung, et al.
Publicado: (2021)

Primary CD8(+) T cells from elite suppressors effectively eliminate non-productively HIV-1 infected resting and activated CD4(+) T cells
por: Buckheit, Robert W, et al.
Publicado: (2013)

Endothelial Gata6 deletion reduces monocyte recruitment and proinflammatory macrophage formation and attenuates atherosclerosis through Cmpk2-Nlrp3 pathways
por: Wu, Wenrun, et al.
Publicado: (2023)

Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network
por: Li, Wan, et al.
Publicado: (2019)

CD8(+) T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants
por: Pohlmeyer, Christopher W, et al.
Publicado: (2013)

Correction: Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network
por: Li, Wan, et al.
Publicado: (2020)

Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay
por: Laird, Gregory M., et al.
Publicado: (2013)

Viral suppression of multiple escape mutants by de novo CD8(+ )T cell responses in a human immunodeficiency virus-1 Infected elite suppressor
por: O'Connell, Karen A, et al.
Publicado: (2011)

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors
por: Salgado, Maria, et al.
Publicado: (2010)

Downregulation of Bcl-2 sensitises interferon-resistant renal cancer cells to Fas
por: Kelly, J D, et al.
Publicado: (2004)

Circular RNA circ‐CMPK1 contributes to cell proliferation of non‐small cell lung cancer by elevating cyclin D1 via sponging miR‐302e
por: Cui, Dong, et al.
Publicado: (2019)

Corrigendum to “Endothelial Gata6 deletion reduces monocyte recruitment and proinflammatory macrophage formation and attenuates atherosclerosis through Cmpk2-Nlrp3 pathways” [Redox Biol. 64 (2023) 102775]
por: Wu, Wenrun, et al.
Publicado: (2023)

Mechanism of delayed cell death following simultaneous CRISPR-Cas9 targeting in pancreatic cancers
por: Teh, Selina Shiqing K., et al.
Publicado: (2023)

Contrasting roles for G-quadruplexes in regulating human Bcl-2 and virus homologues KSHV KS-Bcl-2 and EBV BHRF1
por: Kumar, Shivani, et al.
Publicado: (2022)

Psychostimulant Use Disorder, an Unmet Therapeutic Goal: Can Modafinil Narrow the Gap?
por: Hersey, Melinda, et al.
Publicado: (2021)

Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1
por: El-Diwany, Ramy, et al.
Publicado: (2017)

Thyroid hormone increases fatty acid use in fetal ovine cardiac myocytes
por: Chattergoon, Natasha, et al.
Publicado: (2023)

Unusual presentation of choriocarcinoma
por: Balagopal, PG, et al.
Publicado: (2003)

The prognostic significance of apoptosis-associated proteins BCL-2, BAX and BCL-X in clinical nephroblastoma
por: Ghanem, M A, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_uamku32dosktjqrr8d1ivo9aat