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Noncoding RNA-nucleated heterochromatin spreading is intrinsically labile and requires accessory elements for epigenetic stability

The heterochromatin spreading reaction is a central contributor to the formation of gene-repressive structures, which are re-established with high positional precision, or fidelity, following replication. How the spreading reaction contributes to this fidelity is not clear. To resolve the origins of...

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Detalles Bibliográficos
Autores principales: Greenstein, R A, Jones, Stephen K, Spivey, Eric C, Rybarski, James R, Finkelstein, Ilya J, Al-Sady, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070336/
https://www.ncbi.nlm.nih.gov/pubmed/30020075
http://dx.doi.org/10.7554/eLife.32948