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[(11)C]SCH23390 binding to the D(1)-dopamine receptor in the human brain—a comparison of manual and automated methods for image analysis

BACKGROUND: The D(1)-dopamine receptor radioligand [(11)C]SCH23390 has been frequently used in PET studies. In drug-naïve patients with schizophrenia, the findings have been inconsistent, with decreases, increases, and no change in the frontal cortex D(1)-dopamine receptors. While these discrepancie...

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Detalles Bibliográficos
Autores principales: Stenkrona, Per, Matheson, Granville J., Cervenka, Simon, Sigray, Pontus Plavén, Halldin, Christer, Farde, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070454/
https://www.ncbi.nlm.nih.gov/pubmed/30069645
http://dx.doi.org/10.1186/s13550-018-0416-2