Enhancement of adenovirus infection and adenoviral vector-mediated gene delivery by bromodomain inhibitor JQ1

Adenovirus-based vectors are among the most commonly used platforms for gene delivery and gene therapy studies. One of the obstacles for potential application is dose-related toxicity. We show here that adenovirus infection and Ad-mediated gene delivery can be enhanced by inhibitors of bromodomain a...

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Detalles Bibliográficos
Autores principales: Lv, Baojie, Li, Jingjing, Li, Meng, Zhuo, Yujie, Ren, Ke, Li, Erguang, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070498/
https://www.ncbi.nlm.nih.gov/pubmed/30068949
http://dx.doi.org/10.1038/s41598-018-28421-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070498/
https://www.ncbi.nlm.nih.gov/pubmed/30068949
http://dx.doi.org/10.1038/s41598-018-28421-x

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