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Characterizing the activity of abundant, diverse and active CRISPR-Cas systems in lactobacilli

CRISPR-Cas systems provide immunity against phages and plasmids in bacteria and archaea. Despite the popularity of CRISPR-Cas9 based genome editing, few endogenous systems have been characterized to date. Here, we sampled 1,262 publically available lactobacilli genomes found them to be enriched with...

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Detalles Bibliográficos
Autores principales: Crawley, Alexandra B., Henriksen, Emily D., Stout, Emily, Brandt, Katelyn, Barrangou, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070500/
https://www.ncbi.nlm.nih.gov/pubmed/30068963
http://dx.doi.org/10.1038/s41598-018-29746-3