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Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody
Immunoglobulin E (IgE) antibodies play a central role in the allergic response: interaction with FcεRI on mast cells and basophils leads to immediate hypersensitivity reactions upon allergen challenge, while interaction with CD23/FcεRII, expressed on a variety of cells, regulates IgE synthesis among...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070508/ https://www.ncbi.nlm.nih.gov/pubmed/30069035 http://dx.doi.org/10.1038/s41598-018-29664-4 |