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Searching the overlap between network modules with specific betweeness (S2B) and its application to cross-disease analysis

Discovering disease-associated genes (DG) is strategic for understanding pathological mechanisms. DGs form modules in protein interaction networks and diseases with common phenotypes share more DGs or have more closely interacting DGs. This prompted the development of Specific Betweenness (S2B) to f...

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Detalles Bibliográficos
Autores principales: Garcia-Vaquero, Marina L., Gama-Carvalho, Margarida, Rivas, Javier De Las, Pinto, Francisco R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070533/
https://www.ncbi.nlm.nih.gov/pubmed/30068933
http://dx.doi.org/10.1038/s41598-018-29990-7