Histone deacetylase inhibitor, CG200745 attenuates renal fibrosis in obstructive kidney disease

Tubulointerstitial fibrosis is a common feature of kidney disease. Histone deacetylase (HDAC) inhibitors have been reported to attenuate renal fibrosis progression. Here, we investigated the effect of CG200745, a novel HDAC inhibitor, on renal fibrosis development in a mouse model of unilateral uret...

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Detalles Bibliográficos
Autores principales: Choi, Hong Sang, Song, Ji Hong, Kim, In Jin, Joo, Soo Yeon, Eom, Gwang Hyeon, Kim, Inkyeom, Cha, Hyunju, Cho, Joong Myung, Ma, Seong Kwon, Kim, Soo Wan, Bae, Eun Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070546/
https://www.ncbi.nlm.nih.gov/pubmed/30068917
http://dx.doi.org/10.1038/s41598-018-30008-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070546/
https://www.ncbi.nlm.nih.gov/pubmed/30068917
http://dx.doi.org/10.1038/s41598-018-30008-5

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