A positive feedback loop bi-stably activates fibroblasts

Although fibroblasts are dormant in normal tissue, they exhibit explosive activation during wound healing and perpetual activation in pathologic fibrosis and cancer stroma. The key regulatory network controlling these fibroblast dynamics is still unknown. Here, we report that Twist1, a key regulator...

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Detalles Bibliográficos
Autores principales: Yeo, So-Young, Lee, Keun-Woo, Shin, Dongkwan, An, Sugyun, Cho, Kwang-Hyun, Kim, Seok-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070563/
https://www.ncbi.nlm.nih.gov/pubmed/30069061
http://dx.doi.org/10.1038/s41467-018-05274-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070563/
https://www.ncbi.nlm.nih.gov/pubmed/30069061
http://dx.doi.org/10.1038/s41467-018-05274-6

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