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Overexpression of OqxAB and MacAB efflux pumps contributes to eravacycline resistance and heteroresistance in clinical isolates of Klebsiella pneumoniae

This study investigated the characteristics and mechanisms of eravacycline resistance and heteroresistance in clinical Klebsiella pneumoniae isolates. A total of 393 clinical K. pneumoniae isolates were collected and subjected to eravacycline and tigecycline MIC determinations using the agar dilutio...

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Detalles Bibliográficos
Autores principales: Zheng, Jin-xin, Lin, Zhi-wei, Sun, Xiang, Lin, Wei-hong, Chen, Zhong, Wu, Yang, Qi, Guo-bin, Deng, Qi-wen, Qu, Di, Yu, Zhi-jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070572/
https://www.ncbi.nlm.nih.gov/pubmed/30068997
http://dx.doi.org/10.1038/s41426-018-0141-y