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Optimized Threshold Inference for Partitioning of Clones From High-Throughput B Cell Repertoire Sequencing Data
During adaptive immune responses, activated B cells expand and undergo somatic hypermutation of their B cell receptor (BCR), forming a clone of diversified cells that can be related back to a common ancestor. Identification of B cell clones from high-throughput Adaptive Immune Receptor Repertoire se...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070604/ https://www.ncbi.nlm.nih.gov/pubmed/30093903 http://dx.doi.org/10.3389/fimmu.2018.01687 |