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An in Vivo Mouse Model to Investigate the Effect of Local Anesthetic Nanomedicines on Axonal Conduction and Excitability

Peripheral nerve blocks (PNBs) using local anesthetic (LA) are superior to systemic analgesia for management of post-operative pain. An insufficiently short PNB duration following single-shot LA can be optimized by development of extended release formulations among which liposomes have been shown to...

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Detalles Bibliográficos
Autores principales: Moldovan, Mihai, Alvarez, Susana, Rothe, Christian, Andresen, Thomas L., Urquhart, Andrew, Lange, Kai H. W., Krarup, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070635/
https://www.ncbi.nlm.nih.gov/pubmed/30093852
http://dx.doi.org/10.3389/fnins.2018.00494