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An in Vivo Mouse Model to Investigate the Effect of Local Anesthetic Nanomedicines on Axonal Conduction and Excitability
Peripheral nerve blocks (PNBs) using local anesthetic (LA) are superior to systemic analgesia for management of post-operative pain. An insufficiently short PNB duration following single-shot LA can be optimized by development of extended release formulations among which liposomes have been shown to...
Autores principales: | Moldovan, Mihai, Alvarez, Susana, Rothe, Christian, Andresen, Thomas L., Urquhart, Andrew, Lange, Kai H. W., Krarup, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070635/ https://www.ncbi.nlm.nih.gov/pubmed/30093852 http://dx.doi.org/10.3389/fnins.2018.00494 |
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