Structural Components for Amplification of Positive and Negative Strand VEEV Splitzicons

RNA is a promising nucleic acid technology for both vaccines and therapeutics, and replicon RNA has gained traction as a next-generation RNA modality. Replicon RNA self-amplifies using a replicase complex derived from alphaviral non-structural proteins and yields higher protein expression than a sim...

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Detalles Bibliográficos
Autores principales: Blakney, Anna K., McKay, Paul F., Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070733/
https://www.ncbi.nlm.nih.gov/pubmed/30094239
http://dx.doi.org/10.3389/fmolb.2018.00071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070733/
https://www.ncbi.nlm.nih.gov/pubmed/30094239
http://dx.doi.org/10.3389/fmolb.2018.00071

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