The HIV-1 Reverse Transcriptase A62V Mutation Influences Replication Fidelity and Viral Fitness in the Context of Multi-Drug-Resistant Mutations

Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance arises from mutation fixation in the viral genome during antiretroviral therapy. Primary mutations directly confer antiviral drug resistance, while secondary mutations arise that do not confer drug resistance. The A62V amino ac...

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Detalles Bibliográficos
Autores principales: Maldonado, José O., Mansky, Louis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070896/
https://www.ncbi.nlm.nih.gov/pubmed/30029500
http://dx.doi.org/10.3390/v10070376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070896/
https://www.ncbi.nlm.nih.gov/pubmed/30029500
http://dx.doi.org/10.3390/v10070376

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