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Somatostatin Analogue Treatment Primarily Induce miRNA Expression Changes and Up-Regulates Growth Inhibitory miR-7 and miR-148a in Neuroendocrine Cells

Somatostatin (SST) analogues are used to control the proliferation and symptoms of neuroendocrine tumors (NETs). MicroRNAs (miRNA) are small non-coding RNAs that modulate posttranscriptional gene expression. We wanted to characterize the miRNAs operating under the control of SST to elucidate to what...

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Detalles Bibliográficos
Autores principales: Døssing, Kristina B. V., Kjær, Christina, Vikeså, Jonas, Binderup, Tina, Knigge, Ulrich, Culler, Michael D., Kjær, Andreas, Federspiel, Birgitte, Friis-Hansen, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070923/
https://www.ncbi.nlm.nih.gov/pubmed/29973528
http://dx.doi.org/10.3390/genes9070337