Establishment of a New Zealand White Rabbit Model for Lethal Toxin (LT) Challenge and Efficacy of Monoclonal Antibody 5E11 in the LT-Challenged Rabbit Model

Anthrax caused by Bacillus anthracis is a lethal infectious disease, especially when inhaled, and the mortality rate approaches 100% without treatment. The anthrax antitoxin monoclonal antibody (MAb) 5E11 is a humanized antibody that targets the anthrax protective antigen (PA). The efficacy of 5E11...

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Detalles Bibliográficos
Autores principales: Zhang, Duanyang, Liu, Weicen, Wen, Zhonghua, Li, Bing, Liu, Shuling, Li, Jianmin, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071005/
https://www.ncbi.nlm.nih.gov/pubmed/30002351
http://dx.doi.org/10.3390/toxins10070289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071005/
https://www.ncbi.nlm.nih.gov/pubmed/30002351
http://dx.doi.org/10.3390/toxins10070289

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