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Establishment of a New Zealand White Rabbit Model for Lethal Toxin (LT) Challenge and Efficacy of Monoclonal Antibody 5E11 in the LT-Challenged Rabbit Model
Anthrax caused by Bacillus anthracis is a lethal infectious disease, especially when inhaled, and the mortality rate approaches 100% without treatment. The anthrax antitoxin monoclonal antibody (MAb) 5E11 is a humanized antibody that targets the anthrax protective antigen (PA). The efficacy of 5E11...
Autores principales: | Zhang, Duanyang, Liu, Weicen, Wen, Zhonghua, Li, Bing, Liu, Shuling, Li, Jianmin, Chen, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071005/ https://www.ncbi.nlm.nih.gov/pubmed/30002351 http://dx.doi.org/10.3390/toxins10070289 |
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