Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models

Elements of the hypoxia inducible factor (HIF) transcriptional system, a key regulator of the cellular hypoxic response, are up-regulated in a range of cancer cells. HIF is fundamentally involved in tumor angiogenesis, invasion, and energy metabolism. Inhibition of the transcriptional activity of HI...

Descripción completa

Detalles Bibliográficos
Autores principales: Harris, Emily M., Strope, Jonathan D., Beedie, Shaunna L., Huang, Phoebe A., Goey, Andrew K. L., Cook, Kristina M., Schofield, Christopher J., Chau, Cindy H., Cadelis, Melissa M., Copp, Brent R., Gustafson, Kirk R., Figg, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071056/
https://www.ncbi.nlm.nih.gov/pubmed/30029505
http://dx.doi.org/10.3390/md16070241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071056/
https://www.ncbi.nlm.nih.gov/pubmed/30029505
http://dx.doi.org/10.3390/md16070241

Ejemplares similares