Burkholderia Lethal Factor 1, a Novel Anti-Cancer Toxin, Demonstrates Selective Cytotoxicity in MYCN-Amplified Neuroblastoma Cells

Immunotoxins are being investigated as anti-cancer therapies and consist of a cytotoxic enzyme fused to a cancer targeting antibody. All currently used toxins function via the inhibition of protein synthesis, making them highly potent in both healthy and transformed cells. This non-specific cell kil...

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Detalles Bibliográficos
Autores principales: Rust, Aleksander, Shah, Sajid, Hautbergue, Guillaume M., Davletov, Bazbek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071135/
https://www.ncbi.nlm.nih.gov/pubmed/29954071
http://dx.doi.org/10.3390/toxins10070261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071135/
https://www.ncbi.nlm.nih.gov/pubmed/29954071
http://dx.doi.org/10.3390/toxins10070261

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