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Nausea-Induced 5-HT Release in the Interoceptive Insular Cortex and Regulation by Monoacylglycerol Lipase (MAGL) Inhibition and Cannabidiol

Using the rat conditioned gaping model of nausea, the interoceptive insular cortex (IIC) has been identified as a critical site for the regulation of lithium chloride (LiCl)-induced nausea. Indirect evidence supports a model where serotonin (5-HT) acts on postsynaptic 5-HT(3) receptors and its relea...

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Detalles Bibliográficos
Autores principales: Limebeer, Cheryl L., Rock, Erin M., Sharkey, Keith A., Parker, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071201/
https://www.ncbi.nlm.nih.gov/pubmed/30073198
http://dx.doi.org/10.1523/ENEURO.0256-18.2018