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Nausea-Induced 5-HT Release in the Interoceptive Insular Cortex and Regulation by Monoacylglycerol Lipase (MAGL) Inhibition and Cannabidiol
Using the rat conditioned gaping model of nausea, the interoceptive insular cortex (IIC) has been identified as a critical site for the regulation of lithium chloride (LiCl)-induced nausea. Indirect evidence supports a model where serotonin (5-HT) acts on postsynaptic 5-HT(3) receptors and its relea...
Autores principales: | Limebeer, Cheryl L., Rock, Erin M., Sharkey, Keith A., Parker, Linda A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071201/ https://www.ncbi.nlm.nih.gov/pubmed/30073198 http://dx.doi.org/10.1523/ENEURO.0256-18.2018 |
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