Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery

Cortical spreading depression (CSD) in the CNS is suggested as a common mechanism contributing to headache. Despite strong evidence for CNS involvement in headache disorders, drug development for headache disorders remains focused on peripheral targets. Difficulty in delivering drugs across the bloo...

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Detalles Bibliográficos
Autores principales: Cottier, Karissa E., Galloway, Emily A., Calabrese, Elisa C., Tome, Margaret E., Liktor-Busa, Erika, Kim, John, Davis, Thomas P., Vanderah, Todd W., Largent-Milnes, Tally M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071204/
https://www.ncbi.nlm.nih.gov/pubmed/30073201
http://dx.doi.org/10.1523/ENEURO.0116-18.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071204/
https://www.ncbi.nlm.nih.gov/pubmed/30073201
http://dx.doi.org/10.1523/ENEURO.0116-18.2018

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