Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism

Antimetabolites, in particular nucleobase and nucleoside analogues, are cytotoxic drugs that, starting from the small field of paediatric oncology, in combination with other chemotherapeutics, have revolutionised clinical oncology and transformed cancer into a curable disease. However, even though c...

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Detalles Bibliográficos
Autores principales: Tsesmetzis, Nikolaos, Paulin, Cynthia B. J., Rudd, Sean G., Herold, Nikolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071274/
https://www.ncbi.nlm.nih.gov/pubmed/30041457
http://dx.doi.org/10.3390/cancers10070240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071274/
https://www.ncbi.nlm.nih.gov/pubmed/30041457
http://dx.doi.org/10.3390/cancers10070240

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