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Role of p53 in the Regulation of the Inflammatory Tumor Microenvironment and Tumor Suppression

p53 has functional roles in tumor suppression as a guardian of the genome, surveillant of oncogenic cell transformation, and as recently demonstrated, a regulator of intracellular metabolism. Accumulating evidence has shown that the tumor microenvironment, accompanied by inflammation and tissue remo...

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Detalles Bibliográficos
Autores principales: Uehara, Ikuno, Tanaka, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071291/
https://www.ncbi.nlm.nih.gov/pubmed/29954119
http://dx.doi.org/10.3390/cancers10070219