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Gene Fusion in Malignant Glioma: An Emerging Target for Next-Generation Personalized Treatment

Malignant gliomas are heterogeneous diseases in genetic basis. The development of sequencing techniques has identified many gene rearrangements encoding novel oncogenic fusions in malignant glioma to date. Understanding the gene fusions and how they regulate cellular processes in different subtypes...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Wang, Hongxiang, Huang, Xiaoquan, Li, Weiqing, Huang, Qilin, Yan, Yong, Chen, Juxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071515/
https://www.ncbi.nlm.nih.gov/pubmed/29571074
http://dx.doi.org/10.1016/j.tranon.2018.02.020