Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in Saccharomyces cerevisiae

In 10–15% of cancers, telomere length is maintained by a telomerase-independent, recombination-mediated pathway called alternative lengthening of telomeres (ALT). ALT mechanisms were first seen, and have been best studied, in telomerase-null Saccharomyces cerevisiae cells called “survivors”. There a...

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Detalles Bibliográficos
Autores principales: van Mourik, Paula M., de Jong, Jannie, Sharma, Sushma, Kavšek, Alan, Chabes, Andrei, Chang, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Mutant Screen Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071591/
https://www.ncbi.nlm.nih.gov/pubmed/29848621
http://dx.doi.org/10.1534/g3.118.200280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071591/
https://www.ncbi.nlm.nih.gov/pubmed/29848621
http://dx.doi.org/10.1534/g3.118.200280

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