Targeted Chromosomal Rearrangements via Combinatorial Use of CRISPR/Cas9 and Cre/LoxP Technologies in Caenorhabditis elegans

Rearranged chromosomes have been applied to construct genetic balancers to manipulate essential genes in C. elegans. Although much effort has been put into constructing balancer chromosomes, approximately 6% (map units) of the C. elegans genome has not been covered, and this area lies mostly in pair...

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Detalles Bibliográficos
Autores principales: Chen, Xiangyang, Liao, Shimiao, Huang, Xinya, Xu, Ting, Feng, Xuezhu, Guang, Shouhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071600/
https://www.ncbi.nlm.nih.gov/pubmed/29950430
http://dx.doi.org/10.1534/g3.118.200473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071600/
https://www.ncbi.nlm.nih.gov/pubmed/29950430
http://dx.doi.org/10.1534/g3.118.200473

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