A common pattern of DNase I footprinting throughout the human mtDNA unveils clues for a chromatin-like organization

Human mitochondrial DNA (mtDNA) is believed to lack chromatin and histones. Instead, it is coated solely by the transcription factor TFAM. We asked whether mtDNA packaging is more regulated than once thought. To address this, we analyzed DNase-seq experiments in 324 human cell types and found, for t...

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Detalles Bibliográficos
Autores principales: Blumberg, Amit, Danko, Charles G., Kundaje, Anshul, Mishmar, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071632/
https://www.ncbi.nlm.nih.gov/pubmed/30002158
http://dx.doi.org/10.1101/gr.230409.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071632/
https://www.ncbi.nlm.nih.gov/pubmed/30002158
http://dx.doi.org/10.1101/gr.230409.117

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