A comprehensive characterization of cis-acting splicing-associated variants in human cancer

Although many driver mutations are thought to promote carcinogenesis via abnormal splicing, the landscape of splicing-associated variants (SAVs) remains unknown due to the complexity of splicing abnormalities. Here, we developed a statistical framework to systematically identify SAVs disrupting or n...

Descripción completa

Detalles Bibliográficos
Autores principales: Shiraishi, Yuichi, Kataoka, Keisuke, Chiba, Kenichi, Okada, Ai, Kogure, Yasunori, Tanaka, Hiroko, Ogawa, Seishi, Miyano, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071634/
https://www.ncbi.nlm.nih.gov/pubmed/30012835
http://dx.doi.org/10.1101/gr.231951.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071634/
https://www.ncbi.nlm.nih.gov/pubmed/30012835
http://dx.doi.org/10.1101/gr.231951.117

Ejemplares similares