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An atlas of chromatin accessibility in the adult human brain

Most common genetic risk variants associated with neuropsychiatric disease are noncoding and are thought to exert their effects by disrupting the function of cis regulatory elements (CREs), including promoters and enhancers. Within each cell, chromatin is arranged in specific patterns to expose the...

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Detalles Bibliográficos
Autores principales: Fullard, John F., Hauberg, Mads E., Bendl, Jaroslav, Egervari, Gabor, Cirnaru, Maria-Daniela, Reach, Sarah M., Motl, Jan, Ehrlich, Michelle E., Hurd, Yasmin L., Roussos, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071637/
https://www.ncbi.nlm.nih.gov/pubmed/29945882
http://dx.doi.org/10.1101/gr.232488.117