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Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity

Mycobacterium africanum consists of Lineages L5 and L6 of the Mycobacterium tuberculosis complex (MTBC) and causes human tuberculosis in specific regions of Western Africa, but is generally not transmitted in other parts of the world. Since M. africanum is evolutionarily closely placed between the g...

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Detalles Bibliográficos
Autores principales: Ates, Louis S, Dippenaar, Anzaan, Sayes, Fadel, Pawlik, Alexandre, Bouchier, Christiane, Ma, Laurence, Warren, Robin M, Sougakoff, Wladimir, Majlessi, Laleh, van Heijst, Jeroen W J, Brossier, Florence, Brosch, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071665/
https://www.ncbi.nlm.nih.gov/pubmed/30010947
http://dx.doi.org/10.1093/gbe/evy145