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Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases

Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields.

Detalles Bibliográficos
Autores principales: Kasatkina, Svetlana O, Stepanova, Ekaterina E, Dmitriev, Maksim V, Mokrushin, Ivan G, Maslivets, Andrey N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071730/
https://www.ncbi.nlm.nih.gov/pubmed/30112078
http://dx.doi.org/10.3762/bjoc.14.147