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Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases
Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields.
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071730/ https://www.ncbi.nlm.nih.gov/pubmed/30112078 http://dx.doi.org/10.3762/bjoc.14.147 |
| _version_ | 1783343918808563712 |
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| author | Kasatkina, Svetlana O Stepanova, Ekaterina E Dmitriev, Maksim V Mokrushin, Ivan G Maslivets, Andrey N |
| author_facet | Kasatkina, Svetlana O Stepanova, Ekaterina E Dmitriev, Maksim V Mokrushin, Ivan G Maslivets, Andrey N |
| author_sort | Kasatkina, Svetlana O |
| collection | PubMed |
| description | Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields. |
| format | Online Article Text |
| id | pubmed-6071730 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-60717302018-08-15 Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases Kasatkina, Svetlana O Stepanova, Ekaterina E Dmitriev, Maksim V Mokrushin, Ivan G Maslivets, Andrey N Beilstein J Org Chem Full Research Paper Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields. Beilstein-Institut 2018-07-11 /pmc/articles/PMC6071730/ /pubmed/30112078 http://dx.doi.org/10.3762/bjoc.14.147 Text en Copyright © 2018, Kasatkina et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Kasatkina, Svetlana O Stepanova, Ekaterina E Dmitriev, Maksim V Mokrushin, Ivan G Maslivets, Andrey N Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases |
| title | Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases |
| title_full | Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases |
| title_fullStr | Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases |
| title_full_unstemmed | Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases |
| title_short | Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases |
| title_sort | synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by schiff bases |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071730/ https://www.ncbi.nlm.nih.gov/pubmed/30112078 http://dx.doi.org/10.3762/bjoc.14.147 |
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