Effects of Exposure to Acetaminophen and Ibuprofen on Fetal Germ Cell Development in Both Sexes in Rodent and Human Using Multiple Experimental Systems

BACKGROUND: Analgesic exposure during pregnancy may affect aspects of fetal gonadal development that are targeted by endocrine disruptors. OBJECTIVES: We investigated whether therapeutically relevant doses of acetaminophen and ibuprofen affect germ cell (GC) development in human fetal testes/ovaries...

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Detalles Bibliográficos
Autores principales: Hurtado-Gonzalez, Pablo, Anderson, Richard A., Macdonald, Joni, van den Driesche, Sander, Kilcoyne, Karen, Jørgensen, Anne, McKinnell, Chris, Macpherson, Sheila, Sharpe, Richard M., Mitchell, Rod T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071829/
https://www.ncbi.nlm.nih.gov/pubmed/29665328
http://dx.doi.org/10.1289/EHP2307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071829/
https://www.ncbi.nlm.nih.gov/pubmed/29665328
http://dx.doi.org/10.1289/EHP2307

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