Genetically engineered cerebral organoids model brain tumour formation

Brain tumours are among the most lethal and devastating cancers. Their study is limited by genetic heterogeneity and the incompleteness of available laboratory models. Three-dimensional organoid culture models offer innovative possibilities for modelling human disease. Here, we establish a 3D in vit...

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Detalles Bibliográficos
Autores principales: Bian, Shan, Repic, Marko, Guo, Zhenming, Kavirayani, Anoop, Burkard, Thomas, Bagley, Joshua A., Krauditsch, Christian, Knoblich, Jürgen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071863/
https://www.ncbi.nlm.nih.gov/pubmed/30038414
http://dx.doi.org/10.1038/s41592-018-0070-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071863/
https://www.ncbi.nlm.nih.gov/pubmed/30038414
http://dx.doi.org/10.1038/s41592-018-0070-7

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