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Genetically engineered cerebral organoids model brain tumour formation
Brain tumours are among the most lethal and devastating cancers. Their study is limited by genetic heterogeneity and the incompleteness of available laboratory models. Three-dimensional organoid culture models offer innovative possibilities for modelling human disease. Here, we establish a 3D in vit...
Autores principales: | Bian, Shan, Repic, Marko, Guo, Zhenming, Kavirayani, Anoop, Burkard, Thomas, Bagley, Joshua A., Krauditsch, Christian, Knoblich, Jürgen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071863/ https://www.ncbi.nlm.nih.gov/pubmed/30038414 http://dx.doi.org/10.1038/s41592-018-0070-7 |
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