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Structural basis for nucleosome remodeling by the INO80 complex

DNA in the eukaryotic nucleus is packaged in the form of nucleosomes, ~147 base pairs of DNA wrapped around a histone protein octamer. The position and histone composition of nucleosomes is governed by ATP dependent chromatin remodelers1–3 such as the 15 subunit INO80 complex4. INO80 regulates gene...

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Detalles Bibliográficos
Autores principales: Eustermann, Sebastian, Schall, Kevin, Kostrewa, Dirk, Lakomek, Kristina, Strauss, Mike, Moldt, Manuela, Hopfner, Karl-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071913/
https://www.ncbi.nlm.nih.gov/pubmed/29643509
http://dx.doi.org/10.1038/s41586-018-0029-y