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Structural basis for nucleosome remodeling by the INO80 complex
DNA in the eukaryotic nucleus is packaged in the form of nucleosomes, ~147 base pairs of DNA wrapped around a histone protein octamer. The position and histone composition of nucleosomes is governed by ATP dependent chromatin remodelers1–3 such as the 15 subunit INO80 complex4. INO80 regulates gene...
Autores principales: | Eustermann, Sebastian, Schall, Kevin, Kostrewa, Dirk, Lakomek, Kristina, Strauss, Mike, Moldt, Manuela, Hopfner, Karl-Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071913/ https://www.ncbi.nlm.nih.gov/pubmed/29643509 http://dx.doi.org/10.1038/s41586-018-0029-y |
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