Determination and reduction of translocator protein (TSPO) ligand rs6971 discrimination

The 18 kDa translocator protein (TSPO) is a target for development of diagnostic imaging agents for glioblastoma and neuroinflammation. Clinical translation of TSPO imaging agents has been hindered by the presence of a polymorphism, rs6971, which causes a non-conservative substitution of alanine for...

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Detalles Bibliográficos
Autores principales: Sokias, Renee, Werry, Eryn L., Chua, Sook W., Reekie, Tristan A., Munoz, Lenka, Wong, Erick C. N., Ittner, Lars M., Kassiou, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071920/
https://www.ncbi.nlm.nih.gov/pubmed/30108706
http://dx.doi.org/10.1039/c6md00523c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071920/
https://www.ncbi.nlm.nih.gov/pubmed/30108706
http://dx.doi.org/10.1039/c6md00523c

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