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Distinct mechanisms survey the structural integrity of HLA-B*27:05 intracellularly and at the surface

HLA-B*27:05 is associated with the development of autoimmune spondyloarthropathies, but the precise causal relationship between the MHC haplotype and disease pathogenesis is yet to be elucidated. Studies focusing on the structure and cellular trafficking of HLA-B*27:05 implicate several links betwee...

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Detalles Bibliográficos
Autores principales: Hein, Zeynep, Borchert, Britta, Tolba Abualrous, Esam, Springer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071996/
https://www.ncbi.nlm.nih.gov/pubmed/30071035
http://dx.doi.org/10.1371/journal.pone.0200811