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Uptake and tissue accretion of orally administered free carboxylic acid as compared to ethyl ester form of docosahexaenoic acid (DHA) in the rat

AIM: The aim of this study was to compare the plasma exposure and tissue accretion of docosahexaenoic acid (DHA) in response to oral dosing of free carboxylic acid (OM3CA) and ethyl ester (OM3EE) forms. MATERIALS AND METHODS: Sixteen adult male Wistar rats, fed a low-fat, carbohydrate-rich, standard...

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Detalles Bibliográficos
Autores principales: Lindblom, Anna, Ericsson, Cecilia, Hagstedt, Therese, Kjellstedt, Ann, Oscarsson, Jan, Oakes, Nicholas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072001/
https://www.ncbi.nlm.nih.gov/pubmed/30071037
http://dx.doi.org/10.1371/journal.pone.0201367