GDF15 deficiency promotes high fat diet-induced obesity in mice

Pharmacological treatment of recombinant growth differentiation factor 15 (GDF15) proteins reduces body weight in obese rodents and primates. Paradoxically, circulating GDF15 levels are increased in obesity. To investigate the role of endogenous GDF15 in obesity development, we put GDF15 knockout mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran, Thanhvien, Yang, Jingping, Gardner, Jonitha, Xiong, Yumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072047/
https://www.ncbi.nlm.nih.gov/pubmed/30070999
http://dx.doi.org/10.1371/journal.pone.0201584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072047/
https://www.ncbi.nlm.nih.gov/pubmed/30070999
http://dx.doi.org/10.1371/journal.pone.0201584

Ejemplares similares