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A marginalized two-part Beta regression model for microbiome compositional data
In microbiome studies, an important goal is to detect differential abundance of microbes across clinical conditions and treatment options. However, the microbiome compositional data (quantified by relative abundance) are highly skewed, bounded in [0, 1), and often have many zeros. A two-part model i...
Autores principales: | Chai, Haitao, Jiang, Hongmei, Lin, Lu, Liu, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072097/ https://www.ncbi.nlm.nih.gov/pubmed/30036363 http://dx.doi.org/10.1371/journal.pcbi.1006329 |
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