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Alcohol enhances type 1 interferon-α production and mortality in young mice infected with Mycobacterium tuberculosis

In the current study, we used a mouse model and human blood samples to determine the effects of chronic alcohol consumption on immune responses during Mycobacterium tuberculosis (Mtb) infection. Alcohol increased the mortality of young mice but not old mice with Mtb infection. CD11b+Ly6G+ cells are...

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Detalles Bibliográficos
Autores principales: Tripathi, Deepak, Welch, Elwyn, Cheekatla, Satyanarayana Swamy, Radhakrishnan, Rajesh Kumar, Venkatasubramanian, Sambasivan, Paidipally, Padmaja, Van, Abhinav, Samten, Buka, Devalraju, Kamakshi P., Neela, Venkata Sanjeev Kumar, Valluri, Vijaya Lakshmi, Mason, Carol, Nelson, Steve, Vankayalapati, Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072099/
https://www.ncbi.nlm.nih.gov/pubmed/30071107
http://dx.doi.org/10.1371/journal.ppat.1007174