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Alcohol enhances type 1 interferon-α production and mortality in young mice infected with Mycobacterium tuberculosis
In the current study, we used a mouse model and human blood samples to determine the effects of chronic alcohol consumption on immune responses during Mycobacterium tuberculosis (Mtb) infection. Alcohol increased the mortality of young mice but not old mice with Mtb infection. CD11b+Ly6G+ cells are...
Autores principales: | Tripathi, Deepak, Welch, Elwyn, Cheekatla, Satyanarayana Swamy, Radhakrishnan, Rajesh Kumar, Venkatasubramanian, Sambasivan, Paidipally, Padmaja, Van, Abhinav, Samten, Buka, Devalraju, Kamakshi P., Neela, Venkata Sanjeev Kumar, Valluri, Vijaya Lakshmi, Mason, Carol, Nelson, Steve, Vankayalapati, Ramakrishna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072099/ https://www.ncbi.nlm.nih.gov/pubmed/30071107 http://dx.doi.org/10.1371/journal.ppat.1007174 |
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