Accumulation of citrullinated glial fibrillary acidic protein in a mouse model of bile duct ligation-induced hepatic fibrosis

Hepatic stellate cells (HSCs) play pivotal roles in hepatic fibrosis as they synthesize glial fibrillary acidic protein (GFAP), which is increased in activated HSCs. GFAP-expressing HSCs and myofibroblasts accumulate in and around hepatic fibrosis lesions. Peptidylarginine deiminase 2 (PAD2) is resp...

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Detalles Bibliográficos
Autores principales: Kim, Sung-Eun, Park, Ji Won, Kim, Mo-Jong, Jang, Byungki, Jeon, Yong-Chul, Kim, Hee-Jun, Ishigami, Akihito, Kim, Hyoung Su, Suk, Ki Tae, Kim, Dong Joon, Park, Choong Kee, Choi, Eun-Kyoung, Jang, Myoung-Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072123/
https://www.ncbi.nlm.nih.gov/pubmed/30071078
http://dx.doi.org/10.1371/journal.pone.0201744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072123/
https://www.ncbi.nlm.nih.gov/pubmed/30071078
http://dx.doi.org/10.1371/journal.pone.0201744

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