Sclerostin is upregulated in the early stage of chondrogenic differentiation, but not required in endochondral ossification in vitro

Sclerostin is a potent inhibitor of the canonical Wnt signaling pathway. Wnt signaling pathways have multiple roles in the regulation of cartilage development, growth, and maintenance. This study focused on the role of sclerostin in the process of chondrogenic differentiation. We hypothesized that s...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yasuteru, Kumagai, Ken, Imai, Sosuke, Miyatake, Kazuma, Saito, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072128/
https://www.ncbi.nlm.nih.gov/pubmed/30071108
http://dx.doi.org/10.1371/journal.pone.0201839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072128/
https://www.ncbi.nlm.nih.gov/pubmed/30071108
http://dx.doi.org/10.1371/journal.pone.0201839

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