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Transforming growth factor-β1 gene promoter -509C/T polymorphism in association with expression affects colorectal cancer development and depends on gender

It is widely known that sporadic colorectal cancer (CRC) is age-related diseases with higher incidence rate among men. Transforming growth factor-β1 (TGF-β1) is a major immune regulatory cytokine with a great impact and dual role in gastrointestinal carcinogenesis. In this context, the aim of the st...

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Detalles Bibliográficos
Autores principales: Stanilova, Spaska, Stanilov, Noyko, Julianov, Alexander, Manolova, Irena, Miteva, Lyuba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072135/
https://www.ncbi.nlm.nih.gov/pubmed/30071009
http://dx.doi.org/10.1371/journal.pone.0201775